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Route Formulation Dosing Oral Estradiol 2—4 mg daily Parental subcutaneous, intramuscular Estradiol valerate 5—30 mg every 2 weeks Transdermal Estradiol 0. All aforementioned physical changes can, and reportedly do, change the experience of sensation compared to prior to HRT. Spironolactone prevents the formation of androgens in the testes though not in the adrenal glands by inhibiting enzymes involved in androgen production. Experimental and Clinical Endocrinology. Curr Opin Endocrinol Diabetes Obes ; The Two Halves of the Brain: In addition, diabetes is a significant risk factor for cardiovascular disease and may have an important role in raising the risk of cardiovascular morbidity in trans women on estrogen, as this comorbidity has been found to be prevalent among the transgender population
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I will try now that some other projects are out of the way to be more prompt on updating this and adding some new topics. Williams Textbook of Endocrinology. In transgender women on HRT, as in cisgender women during puberty, breast ducts and Cooper's ligaments develop under the influence of estrogen.
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